Friday, July 31, 2009

All I need is lots of p53

It is official now. I signed the protocol and I entered the Phase One study for R7112. It was pouring when I left MSKCC and the rain soaked my copy of the protocol... but I can still read what this drug might do:

We are testing the safety of different doses of a new oral medicine called R7112. We want to find out what R7112 does to you and your cancer, good or bad. R7112 blocks a molecule called "MDM2" in tumor cell. This causes the cell to make more of a molecule called "p53". Large amounts of p53 then cause a tumor cell to self-destruct.

I will tell you more details tomorrow. Right now I am going to dream with large amounts of p53

Good night.

11 comments:

g said...

Well it looks like you had a great time on your vacation. Glad to hear that your are on your way to starting your trial. All good and positive vibes your way my friend with this new phase trail. I hope this trail will be the one that will kick this thing out to mars.
Now, I hope you took those red shoes with you to New York........if anything those shoes will at least bring some sunshine to all the rain.
Take care Elsa........

Got Hope? I Do! said...

Sorry the g is me

tapioca said...

Em frente, Elsinha!
Vai ser desta! Tens aqui uma imensa equipa a torcer por ti.
Beijinhos

Je Vois la Vie en Vert said...

Sweet dreams....

beijinhos

Verdinha

Erin said...

p53p53p53p53p53p53p53p53p53
p53p53p53p53p53p53p53p53p53
p53p53p53p53p53p53p53p53p53
p.s. So glad you had a good vacation.

Erin said...

And can I add that I'm glad you're back? I missed you and i don't even know you. Ohmygosh, does that make me a crazy blog stalker?

CLARINHA said...

Agora é que vai ser de vez....
Beijocas

Gabby said...

TT You're back!!! I missed you sooo much!!! How is the gang doing? My mom and you can talk and my dad and Uncle Ze can watch soccer and me, Muia, and the kitty lover can do stuff...
YAY WHOO YAY WHOO YAY WHOO...

nyleelee said...

Johnny my partner of 20 years. Has had nothing but bad neews and a lot of I'm sorry for the Doctors treating his lipo Sarcoma. He was given 3 months to 2 years to live recently. It totally wiped out his entire spirit. He wont eat drink or speak. It's been 4 days. I don't know what to do anymore. I just sit and cry. For the past year , I have been the driving force for both of us to my surprise. I am finally burnt out, Johnny just wants me to leave him alone. How does he expect me to watch him wither away to nothing? He ask me to find someone else in the DC, VA or MD area that has Lipo Sarcoma, he needs to know he is not alone...................

tapioca said...

sei que começas hoje com o novo tratamento.
em pensamento estamos contigo.
Beijinhos

Kathy said...

Welcome back, Elsa. Looks like you had a good time :) Hope this new trial WORKS..but if you had the tumor removed, what are they measuring?